Aunorubicin resistance proteins existed in P. pentosaceus LI05. One ORF encoded > 자유게시판

Aunorubicin resistance proteins existed in P. pentosaceus LI05. One ORF encoded DrrA, which is part of the ABC transporter complex DrrAB. The other ORF encoded DrrC, which is part of the ABC transporter permease protein. This finding partially reflects the complex interactions between drugs andgut-associated microbes [33]. Both daunorubicin and doxorubicin are antitumor drugs and are thus not suitable for antibacterial applications. Therefore, these two genes will not affect the control of P. pentosaceus LI05. Additionally, there were eight extra putative multifunctional proteins in P. pentosaceus LI05. These included a TetR family transcriptional regulator, an ABC transporter permease, an exonuclease ABC subunit A, a transposase, an acetyl xylan esterase, a PadR family transcriptional regulator, a membrane protein and a TraX family protein.Conclusions Strains of P. pentosaceus are frequently identified in food and in the human gastrointestinal tract and are known to reduce inflammation, encephalopathy, obesity and fatty liver in animals. Therefore, it is imperative to studyLv et al. Gut Pathogens 2014, 6:36 http://www.gutpathogens.com/content/6/1/Page 8 ofTable 4 Genes and their encoded proteins detected in P. pentosaceus LI05 with sequence similarities of less than 50 with sequences from both P. pentosaceus ATCC 25745 and P. pentosaceus SLLocus BB06_RS0102945 BB06_RS0102950 BB06_RS0102955 BB06_RS0102980 BB06_RS0102995 BB06_RS0103035 BB06_RS0103095 BB06_RS0103100 BB06_RS0103110 BB06_RS0103120 BB06_RS0103125 BB06_RS0103130 BB06_RS0103135 BB06_RS0103140 BB06_RS0103155 BB06_RS0103175 BB06_RS0103180 BB06_RS0103200 BB06_RS0103305 BB06_RS0103310 BB06_RS0103315 BB06_RS0103320 BB06_RS0104430 BB06_RS0104450 BB06_RS0104515 BB06_RS0104520 BB06_RS0104600 BB06_RS0104605 BB06_RS0104610 BB06_RS0104645 BB06_RS0104660 BB06_RS0105620 Size (bp) 1,110 912 672 936 678 633 618 2,268 591 468 744 1,248 672 339 1,308 859 561 906 930 660 846 987 1,173 398 768 692 1,374 1,548 1,134 462 5,241 810 Predicted function By BLASTp Type I restriction endonuclease subunit S Integrase Type I restriction-modification system, specificity subunit S Daunorubicin resistance ATP-binding protein DrrA ThiJ/PfpI family protein TraX family protein Transposase Daunorubicin resistance protein DrrC Integrase Ferritin-like DNA-binding protein Glycosyltransferase family 2 ABC transporter permease TetR family transcriptional regulator Transposase Excinuclease ABC subunit A Acetyl xylan esterase PadR family transcriptional regulator Membrane protein Epimerase Capsular polysaccharide biosynthesis protein Glycosyltransferase Polysaccharide PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/16989806 biosynthesis protein Phage integrase family site-specific recombinase Putative prophage repressor Phage protein Replisome organizer Terminase Minor capsid protein Minor capsid protein Capsid protein Tail protein Phage protein Lenalidomide Best BLASTp hit Accession no. WP_000072560.1 WP_006845852.1 WP_003595917.1 YP_004841605.1 WP_010770374.1 YP_006726711.1 YP_005004471.1 WP_003680292.1 WP_004906016.1 BAN08201.1 WP_027822873.1 WP_027822874.1 WP_027822875.1 WP_015474731.1 WP_024862991.1 WP_025478109.1 WP_017552090.1 024625654.1 WP_021357793.1 WP_003680917.1 WP_003638227.1 YP_004889104.1 WP_004165738.1 WP_007289487.1 ERL43462.1 WP_004165758.1 WP_002318686.1 WP_022638369.1 WP_016511174.1 WP_002314916.1 WP_002820753.1 WP_012678830.1 Organism Staphylococcus aureus Weissella koreensis Lactobacillus casei Lactobacillus sanfranciscensis TMW 1.1304 Enterococcus caccae Lactobac.